Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan (100%) Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Rabbit, Opossum, Platypus (93%).
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARHGEF8; guanine nucleotide regulatory protein (oncogene); NET1; NET1A; Neuroepithelial cell-transforming gene 1 protein; neuroepithelioma transforming gene 1; p65 Net1 proto-oncogene protein; Proto-oncogene p65 Net1; Rho guanine nucleotide exchange factor (GEF) 8; Rho guanine nucleotide exchange factor 8; small GTP-binding protein regulator
Gene Aliases: ARHGEF8; NET1; NET1A
UniProt ID: (Human) Q7Z628
Entrez Gene ID: (Human) 10276