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Invitrogen
NET1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-71998
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 356-385 amino acids from the Central region of human NET1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.35 mg/mL
Amount
140 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; guanine nucleotide regulatory protein (oncogene); Net1 homolog; neuroepithelioma transforming gene 1; p65 Net1 proto-oncogene protein; Rho guanine nucleotide exchange factor (GEF) 8; rho guanine nucleotide exchange factor 8; RP11-116G8.1; small GTP-binding protein regulator; unnamed protein product
Gene Aliases: ARHGEF8; mNET1; NET1A
UniProt ID: (Human) Q7Z628, (Mouse) Q9Z206
Entrez Gene ID: (Human) 10276, (Mouse) 56349
positive regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
myoblast migration
cellular response to hydrogen peroxide
cellular response to ionizing radiation
positive regulation of substrate adhesion-dependent cell spreading
regulation of cell growth
signal transduction
regulation of small GTPase mediated signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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