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Product Details
PA5-60648
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (IHC) |
1:20-1:50 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human NEURL1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.05 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2644629 |
Product Specific Information
Immunogen sequence: PDLVSQSGFW AKALPEEFAN EGNIIAFWVD KKGRVFHRIN DSAVMLFFSG VRTADPLWAL VD
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%.
Target Information
NEURL is involved in the determination of cell fate in the neurogenic region of the embryo and plays a role in the determination of cell fate in the central nervous system. NEURL may act as a tumor suppressor whose inactivation could be associated with malignant progression of astrocytic tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase NEURL1; h neu; h neuralized 1; h-neu; h-neuralized 1; neuralized homolog; Neuralized-like protein 1A; RING finger protein 67; RING-type E3 ubiquitin transferase NEURL1
Gene Aliases: bA416N2.1; neu; neu-1; NEUR1; NEURL; NEURL1; NEURL1A; RNF67
UniProt ID: (Human) Q5TDR2
Entrez Gene ID: (Human) 9148
Molecular Function:
ubiquitin-protein ligase
regulation of translation
protein monoubiquitination
Notch signaling pathway
sperm axoneme assembly
nervous system development
brain development
skeletal muscle tissue development
lactation
negative regulation of cell proliferation
sperm motility
positive regulation of apoptotic process
positive regulation of epidermal growth factor-activated receptor activity
negative regulation of Notch signaling pathway
positive regulation of long-term neuronal synaptic plasticity
positive regulation of filopodium assembly
positive regulation of dendritic spine development
cellular response to amino acid stimulus
positive regulation of synapse maturation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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