PA1-23423 detects NFATc1 in human samples.
PA1-23423 has been successfully used in ELISA and Western Blot procedures.
The PA1-23423 immunogen is a synthetic peptide corresponding top residues L(102) S S G H T R P D G A P A(114) of human NFATc1.
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that coordinate the immune response. NFATc is the cytosolic component of NFAT and encoded by a separate gene. Expression of NFATc activates the interleukin (IL-2) promoter in non-T lymphocytes and is required for IL-2 gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calcineurin-dependent 1; cytoplasmic; MGC138448; NF-ATC; NF-ATc1; NFAT trans; NFAT transcription complex cytosolic component; NFAT2; NFATC; NFATC1; nuclear factor of activated T-cells; nuclear factor of activated T-cells 'c'; Nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Gene Aliases: NF-ATC; NF-ATc1.2; NFAT2; NFATC; NFATC1
UniProt ID: (Human) O95644
Entrez Gene ID: (Human) 4772
Molecular Function: transcription factor