This Antibody was verified by IP-mass spectrometry to ensure that the antibody binds to the antigen stated. View Details
PA1-021 detects nuclear factor of activated T-cells 3 (NFAT3) from human cells.
PA1-021 has been successfully used in Western blot immunohistochemistry, immunofluorescence, and immunoprecipitation procedures. By Western blot, this antibody detects an ~150 kDa protein representing NFAT3 in HEK293 cells transfected with the human NFAT3 gene. Immunohistochemical staining of NFAT3 in HEK293 cells transfected with the human NFAT3 gene results in cytoplasmic staining.
The PA1-021 immunogen is a synthetic peptide corresponding to residues C R(887) D L S G F P A P P G E E P P A(902) of human NFAT3. This sequence is 94% conserved with mouse NFAT3. The PA1-021 immunizing peptide (Cat. # PEP-122) is available for use in neutralization and control experiments.
This protein is an adapter or scaffold protein, which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: NF-AT3; NF-ATc4; Nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T-cell transcription factor NFAT3
Gene Aliases: NF-AT3; NF-ATC4; NFAT3; NFATC4
UniProt ID: (Human) Q14934
Entrez Gene ID: (Human) 4776
Molecular Function: transcription factor