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Product Details
17062-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
NFE2L1 Fusion Protein Ag10832 (423-772 aa encoded by BC010623) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.13 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human ESRRG.
Immunogen sequence: NGTANDTAG PELPDPLGGL LDEAMLDEIS LMDLAIEEGF NPVQASQLEE EFDSDSGLSL DSSHSPSSLS SSEGSSSSSS SSSSSSSSAS SSASSSFSEE GAVGYSSDSE TLDLEEAEGA VGYQPEYSKF CRMSYQDPAQ LSCLPYLEHV GHNHTYNMAP SALDSADLPP PSALKKGSKE KQADFLDKQM SRDEHRARAM KIPFTNDKII NLPVEEFNEL LSKYQLSEAQ LSLIRDIRRR GKNKMAAQNC RKRKLDTILN LERDVEDLQR DKARLLREKV EFLRSLRQMK QKVQSLYQEV FGRLRDENGR PYSPSQYALQ YAGDGSVLLI PRTMADQQAR RQERKPKDRR K (423-772 aa encoded by BC010623)
Target Information
This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official symbol of NRF1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endoplasmic reticulum membrane sensor NFE2L1; LCR-F1; Locus control region-factor 1; NF-E2-related factor 1; NFE2-related factor 1; nuclear factor (erythroid-derived 2)-like 1; Nuclear factor erythroid 2-related factor 1; nuclear factor, erythroid 2-like 1; Nuclear factor, erythroid derived 2, like 1; Protein NRF1, p110 form; Protein NRF1, p120 form; TCF-11; transc; Transcription factor 11; transcription factor 11 (basic leucine zipper type); transcription factor HBZ17; transcription factor LCR-F1; Transcription factor NRF1
Gene Aliases: AA408798; AW212678; HBZ17; LCR-F1; Lcrf1; NFE2L1; NRF1; TCF-11; TCF11
UniProt ID: (Human) Q14494, (Mouse) Q61985
Entrez Gene ID: (Human) 4779, (Mouse) 18023
Molecular Function:
basic leucine zipper transcription factor
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
heme biosynthetic process
inflammatory response
anatomical structure morphogenesis
erythrocyte differentiation
cellular response to oxidative stress
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
protein binding
DNA binding
sequence-specific DNA binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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