The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Chicken, Bovine and Golden hamster
NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CCAAT-box-binding transcription factor; CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3; Nuclear factor 1 B-type; nuclear factor 1/B; Nuclear factor I/B; TGGCA-binding protein
Gene Aliases: CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB; NFIB2; NFIB3
UniProt ID: (Human) O00712
Entrez Gene ID: (Human) 4781