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Product Details
BS-8171R
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide derived from human NFIC, amino acids 21-120. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 50% glycerol, 1% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
-20°C |
Target Information
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCAAT-box-binding transcription factor; CTF; KIAA1439; NF-I/C; NF1-C; NFI-A; NFI-B; NFI-C; NFI-X; NFIA; NFIB; NFIX; Nuclear factor 1 C-type; nuclear factor 1-C2; Nuclear factor 1/A; Nuclear factor 1/B; nuclear factor 1/C; Nuclear factor 1/X; Nuclear factor I/C; nuclear factor I/C (CCAAT-binding transcription factor); olfactory epithelium nuclear factor I-C; TGGCA-binding protein
Gene Aliases: 1110019L22Rik; 1500041O16Rik; AA589446; AI746521; CTF; CTF5; NF-I; NF1-C; NFI; NFIC
UniProt ID: (Human) Q9UPK0, (Mouse) P70255
Entrez Gene ID: (Human) 4782, (Mouse) 18029, (Rat) 29228
Molecular Function:
DNA-binding transcription factor
gene-specific transcriptional regulator
negative regulation of transcription from RNA polymerase II promoter
DNA replication
transcription from RNA polymerase II promoter
odontogenesis of dentin-containing tooth
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
sensory perception of smell
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region DNA binding
DNA binding
double-stranded DNA binding
protein binding
Performance Guarantee
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