Immunogen sequence: MYSSPLCLTQ DEFHPFIEAL LPHVRAFAYT WFNLQARKRK YFKKHEKRMS KDEERAVKDE LLGEKPEVKQ KWASRLLAKL RKDIRPECRE DFVLSITGKK APGCVLSNPD QKGKMRRIDC LRQADKVWRL DLVMVILFKG IPLESTDGER LVKAAQCGHP VLCVQPHHIG VAVKELDLYL AYFVRERDAE QSGSPRTGMG SDQEDSKPIT LDTTDFQESF; Positive Samples: HeLa, LO2, MCF-7, DU145, NIH/3T3, mouse liver, mouse skeletal muscle, rat liver; Cellular Location: Nucleus
The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Protein Aliases: CCAAT-box-binding transcription factor; CTF; NF-I/C; NF1-C; NFI-C; Nuclear factor 1 C-type; nuclear factor 1-C2; nuclear factor 1/C; Nuclear factor I/C; nuclear factor I/C (CCAAT-binding transcription factor); olfactory epithelium nuclear factor I-C; TGGCA-binding protein
Gene Aliases: 1110019L22Rik; 1500041O16Rik; AA589446; AI746521; CTF; CTF5; NF-I; NF1-C; NFI; NFIC