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Proteintech
NFIL3 Polyclonal Antibody
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Product Details
11773-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NFIL3 Fusion Protein Ag2380 (113-462 aa encoded by BC008197)
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ATLKAELLS LKLKFGLISS TAYAQEIQKL SNSTAVYFQD YQTSKSNVSS FVDEHEPSMV SSSCISVIKH SPQSSLSDVS EVSSVEHTQE SSVQGSCRSP ENKFQIIKQE PMELESYTRE PRDDRGSYTA SIYQNYMGNS FSGYSHSPPL LQVNRSSSNS PRTSETDDGV VGKSSDGEDE QQVPKGPIHS PVELKHVHAT VVKVPEVNSS ALPHKLRIKA KAMQIKVEAF DNEFEATQKL SSPIDMTSKR HFELEKHSAP SMVHSSLTPF SVQVTNIQDW SLKSEHWHQK ELSGKTQNSF KTGVVEMKDS GYKVSDPENL YLKQGIANLS AEVVSLKRLI ATQPISASDS G (113-462 aa encoded by BC008197)
Target Information
Expression of interleukin-3 (IL3; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995 [PubMed 7565758]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: E4 promoter binding-protein 4; E4 promoter-binding protein 4; Embryo implantation-related NFIL3/E4BP4-like transcription factor; Interleukin-3 promoter transcriptional activator; Interleukin-3-binding protein 1; NF IL3A; nuclear factor interleukin 3 regulated protein; Nuclear factor interleukin-3-regulated protein; OTTHUMP00000021633; Transcriptional activator NF-IL3A
Gene Aliases: AV225605; E4BP4; IL3BP1; NF-IL3A; NFIL3; NFIL3A
UniProt ID: (Human) Q16649, (Mouse) O08750, (Rat) Q6IMZ0
Entrez Gene ID: (Human) 4783, (Mouse) 18030, (Rat) 114519
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
sequence-specific DNA binding
basic leucine zipper transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
immune response
circadian rhythm
positive regulation of gene expression
cellular response to interleukin-4
transcription, DNA-templated
regulation of transcription, DNA-templated
rhythmic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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