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Proteintech
NGFRAP1 Polyclonal Antibody
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Product Details
10446-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NGFRAP1 Fusion Protein Ag0378 (4-111 aa encoded by BC003190)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IHQENEEME QPMQNGEEDR PLGGGEGHQP AGNRRGQARR LAPNFRWAIP NRQINDGMGG DGDDMEIFME EMREIRRKLR ELQLRNCLRI LMGELSNHHD HHDEFCLMP (4-111 aa encoded by BC003190 )
Target Information
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain expressed X-linked 3; Brain-expressed X-linked protein 3; Brain-expressed X-linked protein 3 homolog; granule cell antiserum positive 27; nerve growth factor receptor (TNFRSF16) associated protein 1; nerve growth factor receptor associated protein 1; Nerve growth factor receptor-associated protein 1; Ovarian granulosa cell 13.0 kDa protein HGR74; p75NTR-associated Cell Death Executor; Protein BEX3; rBex3; RP13-349O20.1
Gene Aliases: AL033356; Bex; BEX3; DXS6984E; DXWsu67e; Gcap27; HGR74; NADE; NGFRAP1
UniProt ID: (Human) Q00994, (Rat) Q6PDU5, (Mouse) Q9WTZ9
Entrez Gene ID: (Human) 27018, (Rat) 117089, (Mouse) 12070
extrinsic apoptotic signaling pathway via death domain receptors
activation of cysteine-type endopeptidase activity involved in apoptotic process
multicellular organism development
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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