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NGR2 Polyclonal Antibody
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Product Details
BS-2710R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human IFNGR2, amino acids 241-337.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AF-1; IFN-gamma receptor 2; IFN-gamma-R-beta; IFN-gamma-R2; IFNgR2; Interferon gamma receptor 2; Interferon gamma receptor accessory factor 1; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; Interferon gamma receptor beta-chain; Interferon gamma transducer 1; unnamed protein product
Gene Aliases: AF-1; IFGR2; Ifgt; IFNGR2; IFNGT1; IMD28
UniProt ID: (Human) P38484
Entrez Gene ID: (Human) 3460, (Rat) 360697, (Mouse) 15980
microglial cell activation
cell surface receptor signaling pathway
response to virus
cytokine-mediated signaling pathway
type III interferon-mediated signaling pathway
defense response to virus
interferon-gamma-mediated signaling pathway
cellular response to virus
positive regulation of glutamate receptor signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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