Suggested positive control: antigen standard for MAP3K14 (transient overexpression lysate).
NIK (NF-kB-inducing Kinase) expression leads to IkB kinase activation and induces nuclear translocation of NF-kB. It is involved in regulation of apoptosis, tumorigenesis, inflammation and various autoimmune diseases. In PC12 cells it induces differentiation and prevents apoptosis.
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Protein Aliases: FTDCR1B; HS; HSNIK; Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; NIK; Serine/threonine-protein kinase NIK
Gene Aliases: FTDCR1B; HS; HSNIK; MAP3K14; NIK
UniProt ID: (Human) Q99558
Entrez Gene ID: (Human) 9020