PA5-27912 targets NKIAMRE in WB applications and shows reactivity with Human samples.
The PA5-27912 immunogen is recombinant fragment corresponding to a region within amino acids 46 and 308 of Human NKIAMRE.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: Cyclin-dependent kinase-like 3; NKIAMRE; serine-threonine protein kinase NKIAMRE; Serine/threonine-protein kinase NKIAMRE
Gene Aliases: CDKL3; NKIAMRE
UniProt ID: (Human) Q8IVW4
Entrez Gene ID: (Human) 51265