|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthesized peptide derived from internal of human NLE1.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The antibody detects endogenous levels of total NLE1 protein.
Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival By similarity. Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004). Bienvenut W.V.; Submitted (AUG-2005) to UniProtKB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.