Positive Control: 293T, 293T nuclear extract
Predicted Reactivity: Mouse (96%), Rat (96%), Xenopus laevis (81%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (94%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
NLE1 plays a role in regulating Notch activity, in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. NLE1 is required during embryogenesis for inner mass cell survival.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ10458; Notchless gene homolog; Notchless protein homolog 1
Gene Aliases: HUSSY-07; Nle; NLE1
UniProt ID: (Human) Q9NVX2
Entrez Gene ID: (Human) 54475