This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.
Protein Aliases: angiotensin binding protein; Angiotensin-binding protein; endopeptidase 24.16; MEP; Microsomal endopeptidase; Mitochondrial oligopeptidase M; neurolysin (metallopeptidase M3 family); Neurolysin, mitochondrial; Neurotensin endopeptidase
Gene Aliases: 4930472G13Rik; AGTBP; C79345; EP24.16; KIAA1226; MEP; MOP; NLN
Molecular Function: metalloprotease