This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
In Western blot applications, this antibody detects a band at ~110kDa. A suggested positive control is human peripheral blood leukocyte (pbl) lysate.
PA5-20014 can be used with blocking peptide PEP-0133.
NLRC4 encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
Protein Aliases: CARD, LRR, and NACHT-containing protein; caspase recruitment domain family, member 12; Caspase recruitment domain-containing protein 12; Clan protein; Ice protease-activating factor; ICE-protease activating factor; Ipaf; NLR family CARD domain-containing protein 4; NLR family, CARD domain containing 4; NOD-like receptor C4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
Gene Aliases: AIFEC; CARD12; CLAN; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR2.1; FCAS4; IPAF; NLRC4; UNQ6189/PRO20215
UniProt ID: (Human) Q9NPP4
Entrez Gene ID: (Human) 58484