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Proteintech
NMD3 Polyclonal Antibody
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Product Details
16060-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NMD3 Fusion Protein Ag8894 (154-503 aa encoded by BC013317)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KAVIQVRQK TLHKKTFYYL EQLILKYGMH QNTLRIKEIH DGLDFYYSSK QHAQKMVEFL QCTVPCRYKA SQRLISQDIH SNTYNYKSTF SVEIVPICKD NVVCLSPKLA QSLGNMNQIC VCIRVTSAIH LIDPNTLQVA DIDGSTFWSH PFNSLCHPKQ LEEFIVMECS IVQDIKRAAG AGMISKKHTL GEVWVQKTSE MNTDKQYFCR THLGHLLNPG DLVLGFDLAN CNLNDEHVNK MNSDRVPDVV LIKKSYDRTK RQRRRNWKLK ELARERENMD TDDERQYQDF LEDLEEDEAI RKNVNIYRDS AIPVESDTDD EGAPRISLAE MLEDLHISQD ATGEEGASML T (154-503 aa encoded by BC013317)
Target Information
NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 60S ribosomal export protein NMD3; hNMD3; NMD3 homolog; unnamed protein product
Gene Aliases: C87860; CGI-07; NMD3; RGD1308468
UniProt ID: (Human) Q96D46, (Mouse) Q99L48
Entrez Gene ID: (Human) 51068, (Mouse) 97112, (Rat) 310512
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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