N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: GluN2A; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate NMDA receptor subunit epsilon-1; Glutamate receptor ionotropic NMDA 2A; Glutamate receptor ionotropic, NMDA 2A; Grin2a; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor subunit 2A; N-Methyl-D-Aspartate Receptor Type 2A; NMDAR2A; NR2A
Gene Aliases: GluN2A; Grin2a; NMDAR2A; NR2A
UniProt ID: (Rat) Q00959
Entrez Gene ID: (Rat) 24409