In Western blot, this antibody detects a single ~180 kDa protein representing NR2A in rat brain homogenate. It shows no cross-reactivity with NR2B.
Reconstitute with 50 µL of PBS.
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: GluN2A; GluRepsilon1; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate receptor ionotropic, NMDA 2A; glutamate receptor, ionotropic, N-methyl D-aspartate 2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; N-Methyl-D-Aspartate Receptor Type 2A; NMDAR2A; NR2A
Gene Aliases: EPND; FESD; GluN2A; GRIN2A; LKS; NMDAR2A; NR2A