This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
NM2 is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of human erythrocyte NDP kinase. NDP kinases are involved in the synthesis of nucleoside triphosphates, and NM23 may act in the regulation of signal transduction by complexing with G proteins, causing activation/inactivation of developmental pathways. NEM2 has been identified as a putative tumor suppressor. High expression of mouse NME2 is detected in heart, liver, and kidney, with moderate expression in skeletal muscle, and negligible expression in other mouse tissues examined.
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Protein Aliases: C-myc purine-binding transcription factor PUF; c-myc transcription factor; epididymis secretory sperm binding protein Li 155an; expressed in non-metastatic cells 2; expressed in non-metastatic cells 2 protein; HEL-S-155an; Histidine protein kinase NDKB; NDK B; NDP kinase alpha; NDP kinase B; nm23-H2; nm23-M2; non-metastatic cells 2, protein (NM23) expressed in; non-metastatic cells 2, protein (NM23B) expressed in; Nucleoside diphosphate kinase B; nucleoside-diphosphate kinase 2; nucleotide diphosphate kinase B; P18
Gene Aliases: NDKB; NDPK-B; NDPKB; nm23-2; NM23-H2; nm23-M2; NM23B; NME2; p18-12d; PUF