Immunogen sequence: KINVTEIPDT LREDQMRDKL ELSFSKSRNG GGEVDRVDYD RQSGSAVITF VEIGVADKIL KKKEYPLYIN QTCHRVTVSP YTEIHLKKYQ IFSGTSKRTV LLTGMEGIQM DEEIVEDLIN IHFQRAKNGG GEVDVVKCSL GQPH
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 46%.
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.
Protein Aliases: N-myc (and STAT) interactor; N-myc and STAT interactor; N-myc interactor; N-myc-interactor; Nmi
Gene Aliases: NMI
UniProt ID: (Human) Q13287
Entrez Gene ID: (Human) 9111
Molecular Function: transcription cofactor