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FIGURE: 1 / 1
NMUR2 Antibody (PA5-88771) in WB
Western blot analysis of NMUR2 in extracts of various cell lines. Samples were incubated with NMUR2 Polyclonal antibody (Product # PA5-88771) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-88771
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 326-415 of human NMUR2 (NP_0645523)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805119
Product Specific Information
Immunogen sequence: IYNLLSRRFQ AAFQNVISSF HKQWHSQHDP QLPPAQRNIF LTECHFVELT EDIGPQFPCQ SSMHNSHLPA ALSSEQMSRT NYQSFHFNKT; Positive Samples: SGC-7901, Mouse uterus, Mouse small intestine, Rat uterus; Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; G-protein-coupled receptor FM-4; growth hormone secretagogue receptor family, member 4; Neuromedin-U receptor 2; NMU-R2
Gene Aliases: FM-4; FM4; NMU-R2; NMU2R; NMUR2; TGR-1; TGR1
UniProt ID: (Human) Q9GZQ4, (Rat) Q9ESQ4, (Mouse) Q8BZ39
Entrez Gene ID: (Human) 56923, (Rat) 64042, (Mouse) 216749
reduction of food intake in response to dietary excess
calcium ion transport
regulation of smooth muscle contraction
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
cell-cell signaling
central nervous system development
grooming behavior
feeding behavior
calcium-mediated signaling
activation of phospholipase A2 activity by calcium-mediated signaling
inositol phosphate-mediated signaling
response to pain
arachidonic acid secretion
chloride transmembrane transport
chloride transport
chemical synaptic transmission
signal transduction
G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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