PA5-27834 targets NNT in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27834 immunogen is a recombinant fragment corresponding to a region within amino acids 841 and 1113 of NNT.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
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Protein Aliases: mitochondrial; NAD(P) transhydrogenase; NAD(P) transhydrogenase, mitochondrial; Nicotinamide nucleotide transhydrogenase; Pyridine nucleotide transhydrogenase
Gene Aliases: GCCD4; NNT
UniProt ID: (Human) Q13423
Entrez Gene ID: (Human) 23530