Hamburger Menu Button
Thermo Fisher Scientific Logo
サインイン
アカウントをお持ちですか? アカウントを登録する
  • 製品情報を探す
    • リアルタイムPCR
    • オリゴ、プライマー、プローブ、遺伝子合成
    • クローニング
    • タンパク質解析
    • 細胞培養、トランスフェクション
    • 細胞治療・遺伝子治療
    • 細胞解析
    • 質量分析
    • クロマトグラフィー
    • 分光分析、元素分析、同位体分析
    • 研究分野と使用技法の一覧を見る
  • オンラインオーダー
    • オリゴ、プライマー、プローブ、遺伝子合成
    • TaqManリアルタイムPCRアッセイ
    • カスタムTaqManプローブ&プライマー(国内合成品)
    • miRNA Mimics & Inhibitors
    • Stealth RNAi / siRNA
    • Silencer Select siRNAs
    • カスタムDNAプライマー
    • GeneArt 遺伝子合成
    • GeneArt Strings DNA Fragments
    • TrueGuide CRISPR gRNA
    • オンラインオーダー対象製品を見る
  • サービス
    • 受託サービス
    • 機器サービス & コンプライアンスサービス
    • 技術サービス
    • ピペットサービス
    • ラボプラスチック消耗品サンプル請求
    • サービス保守契約
    • 修理・移転設置
    • ライセンスに関するお問い合わせ
    • イベント、セミナー、トレーニング
    • Unity Lab Services
    • サービス情報の一覧を見る
  • サポート
    • 製品カタログ
    • アプリケーションノート
    • SDSの検索
    • 法規制情報のお問い合わせ
    • 分析証明書
    • Nunc/Nalgene証明書
    • e-learning
    • FAQ・サポート情報
    • ラーニングセンター
    • サポートセンター
    • サポート情報の一覧を見る
  • お客様セグメント
    • バイオテック
    • バイオファーマ
    • CDMO
    • 検査室診断
    • 産業、応用技術
  • お問い合わせ一覧
  • クイックオーダー​
  • ドキュメント、証明書
Thermo Fisher Scientific Logo

Search

Search All
Search button
          • お問い合わせ一覧​
          • クイックオーダー
          • サインイン
            サインイン
            アカウントをお持ちですか? アカウントを登録する
            • Connect Your Lab
            • アカウント
            • カスタム製品とプロジェクト
          • Primary Antibodies ›
          • NOD2 Antibodies

          Invitrogen

          NOD2 Polyclonal Antibody

          View all (15) NOD2 antibodies

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support

          Cite NOD2 Polyclonal Antibody

          Additional Information:
          {{banner.description}}
          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
          NOD2 Polyclonal Antibody

          Product Details

          PA5-23101

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:100-1:2,000
          -

          Immunoprecipitation (IP)

          1:10-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to amino acids 125-162 of human Nod2.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum with 50% glycerol

          Contains

          0.05% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2540628

          Product Specific Information

          The amino acid sequence used as immunogen is 95% homologous in Lar gibbon (Hylobates lar), 97% in chimpanzee.

          Target Information

          NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: caspase recruitment domain family, member 15; caspase recruitment domain protein 15; Caspase recruitment domain-containing protein 15; Inflammatory bowel disease protein 1; NLR family, CARD domain containing 2; NOD 2; NOD-2; NOD-like receptor C2; NOD2 protein; nucleotide-binding oligomerization domain 2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2; Nucleotide-binding oligomerization domain-containing protein 2; unnamed protein product

          View more View less

          Gene Aliases: ACUG; BLAU; BLAUS; CARD15; CD; CLR16.3; F830032C23Rik; IBD1; NLRC2; NOD2; NOD2B; PSORAS1; YAOS

          View more View less

          UniProt ID: (Human) Q9HC29

          View more View less

          Entrez Gene ID: (Human) 64127, (Mouse) 257632

          View more View less

          Function(s)
          nucleotide binding actin binding protein binding ATP binding enzyme binding protein kinase binding Hsp70 protein binding muramyl dipeptide binding pattern recognition receptor activity peptidoglycan binding ubiquitin binding anion binding ADP binding macromolecular complex binding CARD domain binding Hsp90 protein binding carbohydrate derivative binding endodeoxyribonuclease activity, producing 5'-phosphomonoesters non-motor microtubule binding protein scaffold/adaptor protein
          Process(es)
          temperature homeostasis pattern recognition receptor signaling pathway adaptive immune response immune system process positive regulation of dendritic cell antigen processing and presentation positive regulation of cytokine production involved in immune response positive regulation of dendritic cell cytokine production positive regulation of type 2 immune response autophagy defense response I-kappaB kinase/NF-kappaB signaling response to nutrient positive regulation of cell proliferation detection of biotic stimulus detection of bacterium maintenance of gastrointestinal epithelium regulation of appetite response to muramyl dipeptide detection of muramyl dipeptide positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-17 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade intracellular signal transduction intestinal stem cell homeostasis p38MAPK cascade defense response to bacterium regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of MAPK cascade innate immune response positive regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade positive regulation of gamma-delta T cell activation host-mediated regulation of intestinal microbiota composition positive regulation of epithelial cell proliferation regulation of inflammatory response positive regulation of B cell activation positive regulation of NF-kappaB transcription factor activity positive regulation of ERK1 and ERK2 cascade nucleotide-binding oligomerization domain containing 2 signaling pathway protein K63-linked ubiquitination cellular response to lipopolysaccharide cellular response to peptidoglycan cellular response to muramyl dipeptide protein linear polyubiquitination antibacterial innate immune response positive regulation of cytokine production involved in inflammatory response positive regulation of NIK/NF-kappaB signaling positive regulation of mitophagy positive regulation of protein K63-linked ubiquitination negative regulation of macrophage apoptotic process innate immune response in mucosa activation of immune response cytokine production involved in immune response cytokine secretion involved in immune response immunoglobulin production involved in immunoglobulin mediated immune response negative regulation of T cell mediated immunity negative regulation of inflammatory response to antigenic stimulus positive regulation of humoral immune response mediated by circulating immunoglobulin inflammatory response positive regulation of antibacterial peptide biosynthetic process positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria signal transduction positive regulation of protein ubiquitination negative regulation of NF-kappaB transcription factor activity response to peptidoglycan response to lipopolysaccharide negative regulation of interferon-gamma production negative regulation of interleukin-12 production negative regulation of interleukin-18 production negative regulation of interleukin-2 production negative regulation of tumor necrosis factor production positive regulation of interleukin-12 production negative regulation of toll-like receptor 2 signaling pathway activation of MAPK activity involved in innate immune response response to exogenous dsRNA positive regulation of phosphatidylinositol 3-kinase activity negative regulation of growth of symbiont in host positive regulation of innate immune response positive regulation of interleukin-1 beta secretion positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phagocytosis defense response to Gram-positive bacterium protein oligomerization positive regulation of oxidoreductase activity positive regulation of nitric-oxide synthase biosynthetic process positive regulation of prostaglandin-endoperoxide synthase activity macrophage inflammatory protein-1 alpha production regulation of neutrophil chemotaxis positive regulation of prostaglandin-E synthase activity
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          オンラインオーダー Plus Icon Minus Icon
          • オンラインオーダー可能な製品
          • オンラインオーダーに関する個人情報の取扱いについて
          • 特定商取引法に基づく表記
          • 返品について
          • 表示価格について
          • 配送料について
          サポート Plus Icon Minus Icon
          • FAQ、サポート情報
          • お問い合わせ一覧
          • サポートセンター
          • ドキュメント、証明書
          • 研究情報公開
          • Webサイトの問題を報告​
          リソース Plus Icon Minus Icon
          • ラーニングセンター
          • キャンペーン
          • イベント、セミナー
          • Blog
          About Thermo Fisher Plus Icon Minus Icon
          • 企業情報
          • Social Responsibility (CSR)
          • お客さま体験の向上
          • 採用情報 採用情報
          • ニュース
          • 商標
          • ポリシーと通知
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • 標準販売条件
          • 個人情報保護方針
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          Japan flag icon
          Japan

          Your items have has been added!


          Host server : magellan-search-green-b49b87d85-d4j86:80/100.66.77.21:80.
          git-commit: 5b8c860b7cdb41e9cfe07630520f6b51e109d38e
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.47.0-Offline