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Invitrogen
NOLC1 Polyclonal Antibody
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Product Details
PA5-96472
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 400-699 of human NOLC1 (NP_0047322)
Conjugate
Form
Liquid
Concentration
0.75 mg/mL
Amount
75 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VKPAAAPKQP VGGGQKLLTR KADSSSSEEE SSSSEEEKTK KMVATTKPKA TAKAALSLPA KQAPQGSRDS SSDSDSSSSE EEEEKTSKSA VKKKPQKVAG GAAPSKPASA KKGKAESSNS SSSDDSSEEE EEKLKGKGSP RPQAPKANGT SALTAQNGKA AKNSEEEEEE KKKAAVVVSK SGSLKKRKQN EAAKEAETPQ AKKIKLQTPN TFPKRKKGEK RASSPFRRVR EEEIEVDSRV ADNSFDAKRG AAGDWGERAN QVLKFTKGKS FRHEKTKKKR GSYRGGSISV QVNSIKFDSE; Positive Samples: A-549, HeLa, HepG2, MCF7; Cellular Location: Cytoplasm, Nucleus, nucleolus
Target Information
Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 140 kDa nucleolar phosphoprotein; HCV NS5A trans-regulated protein 13; HCV NS5A-transactivated protein 13; Hepatitis C virus NS5A-transactivated protein 13; Nopp140; Nucleolar 130 kDa protein; Nucleolar and coiled-body phosphoprotein 1; nucleolar and coiled-body phosphprotein 1; nucleolar phosphoprotein 140; Nucleolar phosphoprotein p130; nucleolar protein p130; unnamed protein product
Gene Aliases: KIAA0035; NOLC1; NOPP130; NOPP140; NS5ATP13; P130; Srp40
UniProt ID: (Human) Q14978, (Rat) P41777, (Mouse) E9Q5C9
Entrez Gene ID: (Human) 9221, (Rat) 64896, (Mouse) 70769
nucleotide binding
RNA binding
protein binding
ATP binding
GTP binding
protein binding, bridging
protein heterodimerization activity
molecular function inhibitor activity
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
nuclear localization sequence binding
protein domain specific binding
box C/D snoRNA binding
box H/ACA snoRNA binding
poly(A) RNA binding
mitotic cell cycle
rRNA processing
regulation of translation
nucleolus organization
neural crest formation
neural crest cell development
response to osmotic stress
positive regulation of cell proliferation
box H/ACA snoRNA metabolic process
regulation of protein import into nucleus
positive regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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