Immunogen sequence: VKPAAAPKQP VGGGQKLLTR KADSSSSEEE SSSSEEEKTK KMVATTKPKA TAKAALSLPA KQAPQGSRDS SSDSDSSSSE EEEEKTSKSA VKKKPQKVAG GAAPSKPASA KKGKAESSNS SSSDDSSEEE EEKLKGKGSP RPQAPKANGT SALTAQNGKA AKNSEEEEEE KKKAAVVVSK SGSLKKRKQN EAAKEAETPQ AKKIKLQTPN TFPKRKKGEK RASSPFRRVR EEEIEVDSRV ADNSFDAKRG AAGDWGERAN QVLKFTKGKS FRHEKTKKKR GSYRGGSISV QVNSIKFDSE; Positive Samples: A-549, HeLa, HepG2, MCF7; Cellular Location: Cytoplasm, Nucleus, nucleolus
Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.
Protein Aliases: 140 kDa nucleolar phosphoprotein; HCV NS5A trans-regulated protein 13; HCV NS5A-transactivated protein 13; Hepatitis C virus NS5A-transactivated protein 13; Nopp140; Nucleolar 130 kDa protein; Nucleolar and coiled-body phosphoprotein 1; nucleolar and coiled-body phosphprotein 1; nucleolar phosphoprotein 140; Nucleolar phosphoprotein p130; nucleolar protein p130
Gene Aliases: KIAA0035; NOLC1; NOPP130; NOPP140; NS5ATP13; P130