Invitrogen

NOP2 Polyclonal Antibody

1 Published Figure
3 References
View all (5) NOP2 antibodies

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Datasheet
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NOP2 Polyclonal Antibody

Product Details

PA5-59073

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
View 1 publication 1 publication

Affinity Purification (AP)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

C. elegans

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NOP2. Recombinant protein control fragment (Product #RP-97696).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2644741

Product Specific Information

Immunogen sequence: KLMDLFPLSE LVEFLEANEV PRPVTLRTNT LKTRRRDLAQ ALINRGVNLD PLGKWSKTGL VVYDSSVPIG ATPEYLAGH

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

Target Information

NOP2 is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 28S rRNA (cytosine(4447)-C(5))-methyltransferase; MGC117384; MGC149287; MGC149288; NOL1/NOP2/Sun domain family, member 1; NOP2 nucleolar protein homolog; nop2p; Nucleolar protein 1; nucleolar protein 1, 120 kDa; nucleolar protein 1, 120kDa; Nucleolar protein 2 homolog; probable 28S rRNA (cytosine-C(5))-methyltransferase; Proliferating-cell nucleolar antigen p120; Proliferation-associated nucleolar protein p120; putative ribosomal RNA methyltransferase NOP2

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Gene Aliases: 120kDa; A530002O17; NOL1; NOP120; NOP2; NSUN1; p120

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UniProt ID: (Human) P46087

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Entrez Gene ID: (Human) 4839, (Mouse) 110109, (Rat) 314969

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Function(s)
protein binding rRNA (cytosine-C5-)-methyltransferase activity poly(A) RNA binding rRNA (adenine-N6,N6-)-dimethyltransferase activity RNA binding protein C-terminal carboxyl O-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity methyltransferase activity C-methyltransferase activity N-methyltransferase activity O-methyltransferase activity S-methyltransferase activity RNA methyltransferase activity mRNA methyltransferase activity tRNA methyltransferase activity protein methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity rRNA methyltransferase activity rRNA (uridine-2'-O-)-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity rRNA (adenine-N6-)-methyltransferase activity DNA-methyltransferase activity tRNA (guanine-N1-)-methyltransferase activity selenocysteine methyltransferase activity arginine N-methyltransferase activity protein-arginine N-methyltransferase activity lysine N-methyltransferase activity protein-lysine N-methyltransferase activity tRNA (uracil) methyltransferase activity tRNA (guanine) methyltransferase activity tRNA (adenine) methyltransferase activity tRNA (cytosine) methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity rRNA (adenine) methyltransferase activity rRNA (cytosine) methyltransferase activity rRNA (guanine) methyltransferase activity rRNA (uridine) methyltransferase activity transferase activity protein C-terminal leucine carboxyl O-methyltransferase activity 1-phenanthrol methyltransferase activity protein-arginine N5-methyltransferase activity methylarsonite methyltransferase activity dimethylarsinite methyltransferase activity 4,5-dihydroxybenzo(a)pyrene methyltransferase activity 1-hydroxypyrene methyltransferase activity 1-hydroxy-6-methoxypyrene methyltransferase activity demethylmenaquinone methyltransferase activity cobalt-precorrin-6B C5-methyltransferase activity cobalt-precorrin-7 C15-methyltransferase activity cobalt-precorrin-5B C1-methyltransferase activity cobalt-precorrin-3 C17-methyltransferase activity dimethylamine methyltransferase activity hydroxyneurosporene-O-methyltransferase activity tRNA (adenine-57, 58-N(1)-) methyltransferase activity methylamine-specific methylcobalamin:coenzyme M methyltransferase activity trimethylamine methyltransferase activity methanol-specific methylcobalamin:coenzyme M methyltransferase activity monomethylamine methyltransferase activity P-methyltransferase activity Se-methyltransferase activity 2-phytyl-1,4-naphthoquinone methyltransferase activity tRNA (uracil-2'-O-)-methyltransferase activity tRNA (cytosine-2'-O-)-methyltransferase activity phosphomethylethanolamine N-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity rRNA (cytosine-2'-O-)-methyltransferase activity rRNA (cytosine-N4-)-methyltransferase activity trihydroxyferuloyl spermidine O-methyltransferase activity
Process(es)
maturation of LSU-rRNA positive regulation of cell proliferation rRNA base methylation rRNA processing biological_process methylation
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