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Invitrogen

NOTCH4 Polyclonal Antibody

View all (11) NOTCH4 antibodies

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Product Details

PA5-40587

Applications
Tested Dilution
Publications

Western Blot (WB)

0.2-1 µg/mL
-

Immunohistochemistry (IHC)

5 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the middle region of human NOTCH4

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Amount

50 µg

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2605873

Product Specific Information

Peptide sequence: LLLGLGAARE LRDQAGLAPA DVAHQRNHWD LLTLLEGAGP PEARHKATPG

Sequence homology: Cow: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Pig: 100%; Rat: 93%

Target Information

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DAQB-143M3.4; FLJ16302; hNotch4; human homolog of Drosophila Notch; MGC74442; Neurogenic locus notch homolog protein 4; Notch 4; Notch homolog 4; NOTCH3; unnamed protein product

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Gene Aliases: INT3; NOTCH4

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UniProt ID: (Human) Q99466

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Entrez Gene ID: (Human) 4855

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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