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Invitrogen

NOTCH4 Polyclonal Antibody

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NOTCH4 Polyclonal Antibody

Product Details

PA5-96995

Applications
Tested Dilution
Publications

Western Blot (WB)

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein (or fragment)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Amount

42 µg

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2808797

Product Specific Information

Immunogen sequence: PPEARHKATP GREAGPFPRA RTVSVSVPPH GGGALPRCRT LSAGAGPRGG GACLQARTWS VDLAARGGGA YSHCRSLSGV GAGGGPTPRG RRFSAGMRGP RPNPAIMRGR YGVAAGRGGR VSTDDWPCDW VALGACGSAS NIPIPPPCLT PSPERGSPQL DCGPPALQEM PINQGGEGKK; Positive Samples: Mouse kidney; Cellular Location: Cell membrane, Nucleus, Single-pass type I membrane protein

Target Information

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DAQB-143M3.4; FLJ16302; hNotch4; human homolog of Drosophila Notch; MGC74442; Neurogenic locus notch homolog protein 4; Notch 4; Notch gene homolog 4; Notch homolog 4; NOTCH3; unnamed protein product

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Gene Aliases: Int-3; INT3; N4; NOTCH4

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UniProt ID: (Human) Q99466, (Mouse) P31695

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Entrez Gene ID: (Human) 4855, (Rat) 406162, (Mouse) 18132

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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