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Proteintech
NOX3 Polyclonal Antibody
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Product Details
30131-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: GRIVRGQTQD SLSLHNITFC RDRYAEWQTV AQCPVPQFSG KEPSAWKWIL GPVVLYACER IIRFWRFQQE VVITKVVSHP SGVLELHMKK RGFKMAPGQY ILVQCPAISS LEWHPFTLTS APQEDFFSVH IRAAGDWTAA LLEAFGAEGQ ALQEPWSLPR LAVDGPFGTA LTD
Target Information
The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide. NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith. It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GP91-3; gp91phox homolog 3; head-tilt; Mitogenic oxidase 2; MOX-2; NADPH oxidase 3; NADPH oxidase catalytic subunit-like 3; NAPDH oxidase 3; NOX-3; similar to gp91phlox
Gene Aliases: GP91-3; het; MOX-2; MOX2; nmf250; NOX3
UniProt ID: (Human) Q9HBY0, (Mouse) Q672J9
Entrez Gene ID: (Human) 50508, (Mouse) 224480
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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