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|Tested species reactivity||Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues C(75) A Q L R R I G D K V N L R Q K(90) of mouse Noxa.|
|Storage buffer||whole serum|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-18332 detects Noxa from mouse samples.
PA1-18332 has been successfully used in Western blot procedures.
The PA1-18332 immunogen is a synthetic peptide corresponding to residues C(75) A Q L R R I G D K V N L R Q K(90) of mouse Noxa, conjugated to diphtheria toxoid.
Reconstitute with 100 ul of distilled water.
The Bcl-2 family of proteins which regulate apoptosis share identical sequences called Bcl-2 Homology domains (BH1-4). The BH3 proteins, including BID, NOXA, PUMA, BIK, BIM and BAD are all pro-apoptotic and share sequence identity within the amphipathic alpha-helical BH3 region, which is essential for their apoptotic function. NOXA is highly expressed in adult T-cell leukemia cell line.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
adult T cell leukemia-derived PMA-responsive; phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMAIP1; protein Noxa