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Product Details
PA5-65419
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human NPAT. Recombinant protein control fragment (Product #RP-106102).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663286
Product Specific Information
Immunogen sequence: VNQAVSPNFSQ GSAIIIASPV QPVLQGMVGM IPVSVVGQNG NNFSTPPRQV LHMPLTAPVC NRSIPQFPVP PKSQKAQGLR NKPCIGKQVN NLVDSSGHSV
Highest antigen sequence identity to the following orthologs - mouse 83%, rat 85%.
Target Information
Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Nuclear protein of the ataxia telangiectasia mutated locus; Nuclear protein of the ATM locus; nuclear protein, ataxia-telangiectasia locus; nuclear protein, co-activator of histone transcription; p220; Protein NPAT
Gene Aliases: CAND3; E14; E14/NPAT; NPAT; p220
UniProt ID: (Human) Q14207
Entrez Gene ID: (Human) 4863
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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