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Proteintech
NPC1L1 Polyclonal Antibody
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Product Details
28085-1-AP
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NPC1L1 Fusion Protein Ag26277
Conjugate
Form
Liquid
Concentration
450 µg/mL
Amount
67.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Dietary consumption and intestinal cholesterol absorption contribute to plasma cholesterol levels, which factor into the risk of coronary heart disease. Niemann-Pick type C1 Like 1 protein (NPC1L1 or NPC3) is enriched in the small intestine and is found in the brush border membrane of enterocytes. It plays a critical role in absorption of intestinal cholesterol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BC 400-127; cholesterol transporter; Niemann-Pick disease type C1; Niemann-Pick C1-like protein 1; Niemann-Pick C3; Niemann-Pick type C1-like 1 minus exon 15; NPC1 (Niemann-Pick disease, type C1, gene)-like 1; NPC1 like 1; NPC1-like intracellular cholesterol transporter 1; NPC1L1; NPC3; similar to Niemann-Pick C1 protein
Gene Aliases: LDLCQ7; NPC11L1; NPC1L1; SLC65A2
UniProt ID: (Human) Q9UHC9
Entrez Gene ID: (Human) 29881
lipid metabolic process
cholesterol biosynthetic process
steroid metabolic process
cholesterol metabolic process
sterol transport
intestinal cholesterol absorption
cholesterol transport
lipoprotein metabolic process
vitamin E metabolic process
cholesterol homeostasis
vitamin transport
cellular response to sterol depletion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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