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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • NPC1L1 Antibodies

          Invitrogen

          NPC1L1 Polyclonal Antibody

          1 Published Figure
          1 Reference
          View all (5) NPC1L1 antibodies

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          Cite NPC1L1 Polyclonal Antibody

          • Antibody Testing Data (2)
          • Published Figures (1)
          NPC1L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          NPC1L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          NPC1L1 Antibody (PA5-72938) in IHC (P)

          Immunohistochemical analysis of NPC1L1 in human small intestine, enterocytes. Samples were incubated in NPC1L1 polyclonal antibody (Product # PA5-72938). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          NPC1L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NPC1L1 Antibody in Western Blot (WB)
          NPC1L1 Antibody in Western Blot (WB)
          NPC1L1 Polyclonal Antibody

          Product Details

          PA5-72938

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:100
          -

          Immunoprecipitation (IP)

          Assay-Dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide made to an internal region of rat Niemann-Pick type C1 Like-1 (between residues 500-600).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2718792

          Target Information

          Dietary consumption and intestinal cholesterol absorption contribute to plasma cholesterol levels, which factor into the risk of coronary heart disease. Niemann-Pick type C1 Like 1 protein (NPC1L1 or NPC3) is enriched in the small intestine and is found in the brush border membrane of enterocytes. It plays a critical role in absorption of intestinal cholesterol.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: BC 400-127; Niemann-Pick C1-like protein 1; Niemann-Pick C3; Niemann-Pick disease, type C1; Niemann-Pick disease, type C1-like 1; NPC1 (Niemann-Pick disease, type C1, gene)-like 1; NPC1 like 1; NPC1-like 1; NPC1-like intracellular cholesterol transporter 1; NPC1L1; NPC3

          View more View less

          Gene Aliases: 9130221N23Rik; Gm243; NPC11L1; NPC1L1

          View more View less

          UniProt ID: (Human) Q9UHC9, (Rat) Q6T3U3

          View more View less

          Entrez Gene ID: (Human) 29881, (Mouse) 237636, (Rat) 432367

          View more View less

          Function(s)
          protein binding drug binding Rab GTPase binding myosin V binding hedgehog receptor activity
          Process(es)
          cholesterol biosynthetic process sterol transport intestinal cholesterol absorption cholesterol transport lipoprotein metabolic process response to drug lipid metabolic process steroid metabolic process cholesterol metabolic process cholesterol homeostasis signal transduction
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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