Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:20-1:200 | View 3 publications 3 publications |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Product Specifications | |
---|---|
Species Reactivity |
Dog, Human, Mouse, Rat |
Published species |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
NPHP3 Fusion Protein Ag16888 (1-131 aa encoded by BC068082) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.51 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MGTASSLVS PAGGEVIEDT YGAGGGEACE IPVEVKPKAR LLRNSFRRGA GAAAGAGPGS LPRGVGAGGL LGASFKSTGS SVPELEYAAA EYERLRKEYE IFRVSKNQEL LSMGRREAKL DTENKRLRAE LQ (1-131 aa encoded by BC068082)
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cilia and flagella associated protein 31; Meckel syndrome, type 7; Nephrocystin-3; nephronophthisis 3 (adolescent)
Gene Aliases: 3632410F03Rik; AI550417; C230078J01; CFAP31; D330020E01Rik; KIAA2000; MKS7; NPH3; NPHP3; pcy; RGD1563856; RHPD; RHPD1; SLSN3
UniProt ID: (Human) Q7Z494, (Mouse) Q7TNH6
Entrez Gene ID: (Dog) 100856544, (Human) 27031, (Mouse) 74025, (Rat) 363126
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