Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cilia and flagella associated protein 31; Meckel syndrome, type 7; Nephrocystin-3
Gene Aliases: 3632410F03Rik; AI550417; C230078J01; CFAP31; D330020E01Rik; KIAA2000; MKS7; NPH3; NPHP3; pcy; RHPD; RHPD1; SLSN3