Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Pig (100%).
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
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Protein Aliases: EAR-1; EAR1; HRev; NR1D1; nuclear receptor Rev-ErbA-alpha; Nuclear receptor subfamily 1 group D member 1; nuclear receptor subfamily 1, group D, member 1; Rev-erb alpha; Rev-erba; Rev-erbA-alpha; Rev-ErbAalpha; Rev-erbalpha; Reverba; Reverbaalpha; RevErbAlpha; THRA1; THRAL; V-erbA-related protein 1
Gene Aliases: ear-1; EAR1; HREV; NR1D1; THRA1; THRAL
UniProt ID: (Human) P20393
Entrez Gene ID: (Human) 9572