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Proteintech
NR1D2 Polyclonal Antibody
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Product Details
13906-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NR1D2 Fusion Protein Ag4881 (1-351 aa encoded by BC045613)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEVNAGGVI AYISSSSSAS SHASCHSEGS ENSFQSSSSS VPSSPNSSNS DTNGNPKNGD LANIEGILKN DRIDCSMKTS KSSAPGMTKS HSGVTKFSGM VLLCKVCGDV ASGFHYGVHA CEGCKGFFRR SIQQNIQYKK CLKNENCSIM RMNRNRCQQC RFKKCLSVGM SRDAVRFGRI PKREKQRMLI EMQSAMKTMM NSQFSGHLQN DTLVEHHEQT ALPAQEQLRP KPQLEQENIK SSSPPSSDFA KEEVIGMVTR AHKDTFMYNQ EQQENSAESM QPKRGERIRK NMEQYNLNHD HCGNGLSSHF PCSESQQHLN GQFKGRNIMH YPNGHAICIA NGHCMNFSNA YT (1-351 aa encoded by BC045613)
Target Information
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EAR-1R; HZF2; nuclear receptor Rev-ErbA beta variant 1; nuclear receptor Rev-ErbA beta variant 2; Nuclear receptor subfamily 1 group D member 2; nuclear receptor subfamily 1, group D, member 2; Orphan nuclear hormone receptor BD73; Rev-erb alpha-related receptor; Rev-erb-beta; Rev-erba beta; rev-erba-alpha-related receptor; Rev-erbabeta; RVR; V-erbA-related protein 1-related
Gene Aliases: BD73; EAR-1R; NR1D2; RVR
UniProt ID: (Human) Q14995
Entrez Gene ID: (Human) 9975
core promoter sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
C4 zinc finger nuclear receptor
DNA-binding transcription factor
zinc finger transcription factor
gene-specific transcriptional regulator
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
regulation of lipid metabolic process
intracellular receptor signaling pathway
regulation of circadian rhythm
steroid hormone mediated signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
regulation of inflammatory response
lipid homeostasis
regulation of energy homeostasis
regulation of skeletal muscle cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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