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Product Details
PA5-46850
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human NR2F2
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2609134
Product Specific Information
Peptide sequence: KVGMRREAVQ RGRMPPTQPT HGQFALTNGD PLNCHSYLSG YISLLLRAEP
Sequence homology: Cow: 92%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 92%; Zebrafish: 92%
Target Information
This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor related protein 1; Apolipoprotein A-I regulatory protein 1; apolipoprotein AI regulatory protein 1; ARP-1; chicken ovalbumin; chicken ovalbumin upstream promoter transcription factor 2; chicken ovalbumin upstream promoter-transcription factor I; COUP transcription factor 2; COUP transcription factor II; COUP-TF II; COUP-TF2; MGC117452; Nuclear receptor subfamily 2 group F member 2; nuclear receptor subfamily 2, group F, member 2
Gene Aliases: ARP1; CHTD4; COUPTFB; COUPTFII; NF-E3; NR2F1; NR2F2; SVP40; TFCOUP2
UniProt ID: (Human) P24468
Entrez Gene ID: (Human) 7026
Molecular Function:
C4 zinc finger nuclear receptor
negative regulation of transcription from RNA polymerase II promoter
neuron migration
maternal placenta development
negative regulation of endothelial cell proliferation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
lipid metabolic process
signal transduction
skeletal muscle tissue development
fertilization
anterior/posterior pattern specification
radial pattern formation
negative regulation of endothelial cell migration
intracellular receptor signaling pathway
forebrain development
response to estradiol
steroid hormone mediated signaling pathway
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
blood vessel morphogenesis
limb development
placenta blood vessel development
trophoblast giant cell differentiation
regulation of transcription involved in lymphatic endothelial cell fate commitment
retinoic acid binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
transcription corepressor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
protein homodimerization activity
sequence-specific DNA binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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