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NRADD Polyclonal Antibody
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Product Details
OSN00050W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from n-terminal region of mouse Neurotrophin receptor associated death domain (NRADD) conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: NRADD.
Target Information
Modulates NTRK1 signaling. Can activate several intracellular signaling pathways, leading to activation of JUN. Promotes apoptosis. Promotes translocation of SORT1 to the cell membrane, and thereby hinders lysosomal degradation of SOTR1 and promotes its interaction with NGFR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: death domain containing membrane protein NRADD; Death domain-containing membrane protein NRADD; neurotrophin receptor alike death domain protein; Neurotrophin receptor homolog-2; Neurotrophin receptor-alike death domain protein; NRH2; P75-like apoptosis-inducing death domain protein; p75-like apoptosis-inducing death domain protein PLAIDD; PLAIDD
Gene Aliases: 2610311B09Rik; BB104149; Nradd; NRDD; NRH2; PLAIDD
UniProt ID: (Mouse) Q8CJ26, (Rat) Q8K5A9
Entrez Gene ID: (Mouse) 67169, (Rat) 246143
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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