Proteintech

NRCAM Polyclonal Antibody

NRCAM Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 7

NRCAM Antibody (21608-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HEK-293 cells using 21608-1-AP (NRCAM antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

NRCAM Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

21608-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NRCAM Fusion Protein Ag16237 (446-628 aa encoded by BC098401)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EPPRILTPA NTLYQVIANR PALLDCAFFG SPLPTIEWFK GAKGSALHED IYVLHENGTL EIPVAQKDST GTYTCVARNK LGMAKNEVHL EIKDATWIVK QPEYAVVQRG SMVSFECKVK HDHTLSLTVL WLKDNRELPS DERFTVDKDH LVVADVSDDD SGTYTCVANT TLDSVSASAV LSVV (446-628 aa encoded by B C098401)

Target Information

Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

NrCAM secreted by endometrial stromal cells enhances the progestin sensitivity of endometrial cancer cells through epigenetic modulation of PRB.

Cancer gene therapy

Cheng Y,Xie L,Xu Z,Hao M,Yang B,Shan W,Wang Y,Lv Q,Chen X

Sat Oct 01 00:00:00 UTC 2022

An Essential NRP1-Mediated Role for Tagln2 in Gastric Cancer Angiogenesis.

Frontiers in oncology

Jin H,Zheng W,Hou J,Peng H,Zhuo H

Tue Jun 22 00:00:00 UTC 2021

Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR.

Molecular and cellular neurosciences

Chen ZH,Luo XC,Yu CR,Huang L

Thu Oct 01 00:00:00 UTC 2020

CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells.

Stem cell reports

Lupia M,Angiolini F,Bertalot G,Freddi S,Sachsenmeier KF,Chisci E,Kutryb-Zajac B,Confalonieri S,Smolenski RT,Giovannoni R,Colombo N,Bianchi F,Cavallaro U

Tue Apr 10 00:00:00 UTC 2018

CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells.

Stem cell reports

Lupia M,Angiolini F,Bertalot G,Freddi S,Sachsenmeier KF,Chisci E,Kutryb-Zajac B,Confalonieri S,Smolenski RT,Giovannoni R,Colombo N,Bianchi F,Cavallaro U

Tue Apr 10 00:00:00 UTC 2018

Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis.

Molecular & cellular proteomics : MCP

Vartanian S,Ma TP,Lee J,Haverty PM,Kirkpatrick DS,Yu K,Stokoe D

Fri Apr 01 00:00:00 UTC 2016

Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis.

Molecular & cellular proteomics : MCP

Vartanian S,Ma TP,Lee J,Haverty PM,Kirkpatrick DS,Yu K,Stokoe D

Fri Apr 01 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: ankyrin-binding cell adhesion molecule NrCAM; hBravo; mBravo; MGC138845; MGC138846; neuron-glia-CAM-related cell adhesion molecule; Neuronal cell adhesion molecule; Neuronal surface protein Bravo; Ng-CAM-related; NgCAM-related cell adhesion molecule; Nr CAM; Nr-CAM; rBravo

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Gene Aliases: Bravo; C030017F07Rik; C130076O07Rik; KIAA0343; mKIAA0343; NRCAM

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UniProt ID: (Human) Q92823, (Mouse) Q810U4

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Entrez Gene ID: (Human) 4897, (Mouse) 319504, (Rat) 497815

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Function(s)

protein binding ankyrin binding protein binding involved in heterotypic cell-cell adhesion scaffold/adaptor protein

Process(es)

angiogenesis neuron migration axonogenesis axonal fasciculation synapse assembly central nervous system development protein localization single organismal cell-cell adhesion neuronal action potential propagation regulation of axon extension retinal ganglion cell axon guidance heterotypic cell-cell adhesion clustering of voltage-gated sodium channels positive regulation of neuron differentiation cell adhesion axon guidance regulation of neuron projection development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NRCAM Polyclonal Antibody

NRCAM Antibody (21608-1-AP) in ICC/IF

Product Details

21608-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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