PA5-19427 targets NSD3 in ICC/IF, IHC (P), and WB applications and shows reactivity with human samples. For IHC staining, heat mediated antigen retrieval is recommended.
The PA5-19427 immunogen is synthetic peptide derived from residues 500 - 600 of Human NSD3.
PA5-19427 detects NSD3 which has a predicted molecular weight of approximately 72.6 kDa and 161 kDa.
This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP domains. The function of the protein has not been determined. Two alternatively spliced variants have been described.
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Protein Aliases: DC28, DKFZp667H044, FLJ20353, MGC126766, MGC142029, NSD3, pp14328, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; Histone-lysine N-methyltransferase NSD3; nuclear receptor binding SET domain protein 3; Nuclear SET domain-containing protein 3; Protein whistle; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; WHSC1-like protein 1; Wolf-Hirschhorn syndrome candidate 1-like protein 1
Gene Aliases: DC28; NSD3; pp14328; WHISTLE; WHSC1L1
UniProt ID: (Human) Q9BZ95
Entrez Gene ID: (Human) 54904