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          • Primary Antibodies ›
          • NSE2 Antibodies

          Proteintech

          NSMCE2 Polyclonal Antibody

          1 Reference
          View all (12) NSE2 antibodies

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          Cite NSMCE2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (10)
          NSMCE2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          NSMCE2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

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          NSMCE2 Antibody (13627-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using (Product # 13627-1-AP) (NSMCE2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          NSMCE2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NSMCE2 Antibody in Western Blot (WB)
          NSMCE2 Antibody in Western Blot (WB)
          NSMCE2 Antibody in Western Blot (WB)
          NSMCE2 Antibody in Western Blot (WB)
          NSMCE2 Antibody in Western Blot (WB)
          NSMCE2 Antibody in Western Blot (WB)
          NSMCE2 Antibody in Western Blot (WB)
          NSMCE2 Antibody in Western Blot (WB)
          NSMCE2 Antibody in Western Blot (WB)
          NSMCE2 Polyclonal Antibody

          Product Details

          13627-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          NSMCE2 Fusion Protein Ag4545 (1-247 aa encoded by BC032797)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Amount

          19.5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MPGRSSSNS GSTGFISFSG VESALSSLKN FQACINSGMD TASSVALDLV ESQTEVSSEY SMDKAMVEFA TLDRQLNHYV KAVQSTINHV KEERPEKIPD LKLLVEKKFL ALQSKNSDAD FQNNEKFVQF KQQLKELKKQ CGLQADREAD GTEGVDEDII VTQSQTNFTC PITKEEMKKP VKNKVCGHTY EEDAIVRMIE SRQKRKKKAY CPQIGCSHTD IRKSDLIQDE ALRRAIENHN KKRHRHSE (1-247 aa encoded by BC032797)

          Target Information

          This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: E3 SUMO-protein ligase NSE2; E3 SUMO-protein transferase NSE2; FLJ32440; hMMS21; methyl methanesulfonate sensitivity gene 21; MMS21 homolog; Non-SMC element 2 homolog; non-SMC element 2, MMS21 homolog; Non-structural maintenance of chromosomes element 2 homolog; NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase; NSMCE2/PVT1 fusion; PVT1/NSMCE2 fusion; unnamed protein product; zinc finger, MIZ-type containing 7

          View more View less

          Gene Aliases: 1110014D18Rik; AI661537; C8orf36; MMS21; NSE2; NSMCE2; RGD1305156; ZMIZ7

          View more View less

          UniProt ID: (Human) Q96MF7, (Mouse) Q91VT1, (Rat) Q4V8A0

          View more View less

          Entrez Gene ID: (Human) 286053, (Mouse) 68501, (Rat) 299957

          View more View less

          Function(s)
          protein binding zinc ion binding transferase activity SUMO transferase activity metal ion binding SUMO ligase activity UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ligase activity ribosomal S6-glutamic acid ligase activity coenzyme F420-0 gamma-glutamyl ligase activity coenzyme F420-2 alpha-glutamyl ligase activity protein-glycine ligase activity protein-glycine ligase activity, initiating protein-glycine ligase activity, elongating tubulin-glycine ligase activity protein-glutamic acid ligase activity tubulin-glutamic acid ligase activity
          Process(es)
          telomere maintenance via recombination double-strand break repair via homologous recombination DNA repair double-strand break repair via nonhomologous end joining DNA recombination cellular response to DNA damage stimulus protein sumoylation regulation of telomere maintenance positive regulation of maintenance of mitotic sister chromatid cohesion positive regulation of mitotic metaphase/anaphase transition cell division cellular senescence chromatin looping cell cycle mitotic nuclear division
          It has to be done as per old AB suggested Products section.

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