Recommended positive controls: HepG2.
Predicted reactivity: Mouse (88%), Rat (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Protein Aliases: cytokinesis and spindle organization B; Cytospin-B; NSP5; NSP5a3a; NSP5alpha3alpha; Nuclear structure protein 5; Sperm antigen HCMOGT-1; Sperm antigen with calponin homology and coiled-coil domains 1; sperm antigen with calponin-like and coiled coil domains 1; structure protein NSP5a3a; structure protein NSP5a3b; structure protein NSP5b3a; structure protein NSP5b3b
Gene Aliases: CYTSB; HCMOGT-1; HCMOGT1; NSP; NSP5; SPECC1
UniProt ID: (Human) Q5M775
Entrez Gene ID: (Human) 92521