Immunogen sequence: FELEPLPGAV EAVKEMASLQ NTDVFICTSP IKMFKYCPYE KYAWVEKYFG PDFLEQIVLT RDKT
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 97%.
Dephosphorylates specifically the 5' and 2'(3')- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5' nucleotidase, mitochondrial; 5'(3')-deoxyribonucleotidase, mitochondrial; 5',3'-nucleotidase, mitochondrial; 5(3)-deoxyribonucleotidase; Deoxy-5'-nucleotidase 2; dNT-2; mitochondrial 5' nucleotidase
Gene Aliases: dNT-2; DNT2; mdN; NT5M
UniProt ID: (Human) Q9NPB1
Entrez Gene ID: (Human) 56953