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Invitrogen
NTF3 Polyclonal Antibody
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Product Details
PA1-9520
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide based on the human NT3 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
500 µg
Purification
IgY fraction
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-9520 detects NT3 in human and mouse samples.
PA1-9520 has been successfully used in ELISA procedures.
PA1-9520 immunogen is a synthetic peptide based on the human NT3 protein.
Target Information
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HDNF; Nerve growth factor 2; Neurotrophic factor; Neurotrophin-3; NGF-2; NT-3; NTF3; unnamed protein product
Gene Aliases: AI316846; AI835689; HDNF; NGF-2; NGF2; NT-3; NT3; Ntf-3; NTF3
UniProt ID: (Human) P20783, (Mouse) P20181
Entrez Gene ID: (Human) 4908, (Mouse) 18205
positive regulation of receptor internalization
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
cell-cell signaling
nervous system development
positive regulation of cell proliferation
nerve development
positive regulation of cell migration
nerve growth factor signaling pathway
regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
neuron projection morphogenesis
modulation of synaptic transmission
positive chemotaxis
induction of positive chemotaxis
positive regulation of protein kinase B signaling
activation of MAPK activity
neuromuscular synaptic transmission
glial cell fate determination
axon guidance
brain development
peripheral nervous system development
epidermis development
activation of protein kinase B activity
positive regulation of peptidyl-serine phosphorylation
mechanoreceptor differentiation
myelination
regulation of neuron apoptotic process
regulation of neuron differentiation
positive regulation of glial cell differentiation
positive regulation of transcription from RNA polymerase II promoter
enteric nervous system development
neuron development
generation of neurons
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of peptidyl-tyrosine phosphorylation
smooth muscle cell differentiation
activation of GTPase activity
positive regulation of actin cytoskeleton reorganization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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