Immunogen sequence: QPPPSTLPPF LAPEWDLLSP RVVLSRGAPA GPPLLFLLEA GAFRESAGAP ANRSRRGVSE TAPASRRGEL AVCDAVSGWV TDRRTAVDLR GREVEVLGEV PAAGGSPLRQ YFFETRCKAD NAEEGGPGAG GGGCRGVDRR HWVSECKAKQ SYVRALTADA QGRVGWRWIR IDTACVCTLL SRTGRA; Positive Samples: Rat thymus
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
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Protein Aliases: neurotrophic factor 4; neurotrophic factor 5; Neurotrophin 5 (neurotrophin 4/5); neurotrophin 5 (neurotrophin 4/5); Neurotrophin-4; Neurotrophin-5; Neutrophic factor 4; NT-4; NT-5
Gene Aliases: GLC10; GLC1O; NT-4; NT-4/5; NT-5; NT4; NT4P; NT5; NTF4; NTF5