This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: DFLTNMHTSK LIQEDILDTG NDKNGKEEVI KRKIPYILKR QLYENKPRRP
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 70%.
This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Large neuromedin N; Neuromedin N; Neurotensin; Neurotensin/neuromedin N; NmN; NmN-125; NN; NT; pro-neurotensin/neuromedin; Tail peptide
Gene Aliases: NMN-125; NN; NT; NT/N; NTS; NTS1
UniProt ID: (Human) P30990
Entrez Gene ID: (Human) 4922