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Proteintech
NUB1 Polyclonal Antibody
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Product Details
14343-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NUB1 Fusion Protein Ag5668 (252-601 aa encoded by BC046354)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Amount
28.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: YGIALPCLL DADKYFCECC RELLDTVDNY AVLQLDIVWC YFRLEQLECL DDAEKKLNLA QKCFKNCYGE NHQRLVHIKG NCGKEKVLFL RLYLLQGIRN YHSGNDVEAY EYLNKARQLF KELYIDPSKV DNLLQLGFTA QEARLGLRAC DGNVDHAATH ITNRREELAQ IRKEEKEKKR RRLENIRFLK GMGYSTHAAQ QILLSNPQMW WLNDSNPETD NRQESPSQEN IDRLVYMGFD ALVAEAALRV FRGNVQLAAQ TLAHNGGSLP PELPLSPEDS LSPPATSPSD SAGTSSASTD EDMETEAVNE ILEDIPEHEE DYLDSTLEDE EIIIAEYLSY VENRKSATKK N (252-601 aa encoded by BC046354)
Target Information
NYREN18 is a specific down-regulator of the NEDD8 conjugation system. It recruits NEDD8 and its conjugates to the proteasome for degradation. It also interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alternatively spliced; NEDD8 ultimate buster 1; NEDD8 ultimate buster-1; NEDD8-interacting protein; alternatively spliced; Negative regulator of ubiquitin-like proteins 1; NY-REN-18 antigen; Protein BS4; Renal carcinoma antigen NY-REN-18; unnamed protein product
Gene Aliases: 4931404D21Rik; 6330412F12Rik; BS4; NUB1; NUB1L; NY-REN-18; NYREN18
UniProt ID: (Human) Q9Y5A7, (Mouse) P54729
Entrez Gene ID: (Human) 51667, (Rat) 296731, (Mouse) 53312
ubiquitin-dependent protein catabolic process
proteasomal protein catabolic process
protein ubiquitination
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
response to interferon-gamma
response to tumor necrosis factor
proteolysis involved in cellular protein catabolic process
regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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